Clinical Trials
Pioneering research. Early access to tomorrow's treatments. African cancer science, led from Africa.
Research Leadership
Africa Needs African Cancer Data
Historically, the world's most influential cancer trials have enrolled almost no African patients. Yet cancer biology, treatment responses, and disease patterns can differ significantly across populations.
Afri-German's Research Unit runs investigator-initiated and partnership trials specifically designed to generate evidence in our patient population -- closing the data gap and improving care for millions across the continent.
Our trials follow the strictest ethical and scientific standards, are reviewed by our Institutional Review Board, and are conducted in full compliance with ICH-GCP guidelines.
Open to Enrolment
Current Clinical Trials
SENTINEL-AFRI: Immunotherapy Plus Chemotherapy in Advanced Cervical Cancer
Evaluating the efficacy and safety of pembrolizumab combined with platinum-based chemotherapy as first-line treatment for advanced cervical cancer in Sub-Saharan African patients.
Sponsor: Afri-German Oncology in partnership with AORTIC
Key Eligibility Criteria:
PRECISE-NG: Genomic-Guided Therapy in Breast Cancer - A Nigerian Cohort Study
Investigating genomic profiling to guide personalised treatment selection in Nigerian breast cancer patients, comparing standard chemotherapy vs. genomically-matched targeted therapy.
Sponsor: Afri-German Oncology / German Cancer Aid Partnership
Key Eligibility Criteria:
HEPATO-RESOLVE: Sorafenib vs. Lenvatinib in HBV-Associated Hepatocellular Carcinoma
A randomised controlled trial comparing two targeted therapy agents in HBV-associated liver cancer, with a sub-Saharan African patient population that has historically been underrepresented in global HCC trials.
Sponsor: Afri-German Oncology / WHO Africa Regional Oncology Network
Key Eligibility Criteria:
MIND-CANCER-GH: Mindfulness-Based Intervention and Quality of Life in Cancer Patients
Evaluating the impact of an adapted Mindfulness-Based Cancer Recovery programme on quality of life, anxiety, and treatment adherence in Nigerian cancer patients.
Sponsor: Afri-German Oncology / King's College London Global Health Partnership
Key Eligibility Criteria:
Why Participate in a Clinical Trial?
Access Cutting-Edge Treatments
Clinical trial participants often access novel therapies not yet commercially available.
Enhanced Medical Monitoring
Trial participants receive more frequent monitoring and closer medical attention than standard care.
Advance African Oncology
Your participation generates vital data about cancer in African patients, improving care for future generations.
Reduced or Zero Cost
Trial drugs and protocol-related tests are typically provided free of charge to participants.
Expert Research Team
You are cared for by both your oncology team and our dedicated research nurses and coordinators.
Withdraw Any Time
Participation is always voluntary. You may withdraw from a trial at any time without affecting your standard care.
How to Enrol
Express Interest
Contact our research team by phone or email to express interest in a specific trial.
Eligibility Screening
Our research coordinator reviews your medical records against trial eligibility criteria.
Informed Consent
A full explanation of the trial in your language so you can make a fully informed decision. No pressure.
Enrolment
Once you consent and are confirmed eligible, you are officially enrolled and treatment begins.
Our Ethics and Safety Commitments
Contact Our Research Team
Have questions about a trial or want to check your eligibility? Our Research Coordinator is ready to help.